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Waterless technology can replace dialysis and transform kidney treatment

ROSEVILLE, Calif., March 13, 2025 (SEND2PRESS NEWSWIRE) — US Kidney Research Corporation (USKRC) is creating the world’s first waterless blood purification device, a pioneering technology with the capability to replace traditional dialysis machines worldwide. A recent groundbreaking discovery in the design of the device’s ion transport system, a critical component responsible for removing excess ions from the bloodstream, restoring ion balance, and directing these excess elements to the urine, is significantly accelerating progress and bringing the device closer to completion.

Image caption: University of Arkansas Lab – Device CAD Image.

The ion transport system plays a vital role in maintaining essential physiological functions. For individuals with kidney disease, the kidneys often fail to filter out excess ions such as sodium, potassium, and phosphorus, causing dangerous imbalances that can lead to serious health issues.

Reaching this milestone brings US Kidney Research Corporation closer to its ultimate goal of developing an implantable artificial kidney. A waterless device is crucial for the development of an implantable artificial kidney. Dialysis’s reliance on a constant water and dialysate supply makes miniaturization and implantation within the body impossible.

This achievement marks a historic milestone as the first successful development of a waterless ion transport system for a medical blood purification device, something that has never been accomplished before.

CEO Roland Ludlow stated, “Creating an ion transport system is an extremely complex scientific challenge. After years of research and extensive experimentation, our scientists have discovered the method needed to complete the task. Breaking through this barrier is a major leap forward.”

Waterless Advantages: In contrast to traditional dialysis systems that depend on water, disposable components like dialyzers and dialysate solutions, as well as a separate water purification infrastructure, the waterless blood purifying device eliminates the need for these costly items, offering significant savings for healthcare providers. Additionally, the device will incorporate innovative technology, such as real-time patient monitoring and precise control over electrolyte, urea, and fluid removal, ensuring greater accuracy and better outcomes for patients.

Ecological Benefits: The waterless blood purifying device addresses environmental challenges by reducing the carbon footprint. It will greatly reduce the billions of gallons of contaminated water generated by dialysis, minimize dialyzer plastic waste, and lower transport and energy costs associated with production.

MISSION & GOALS

US Kidney Research Corporation is dedicated to:

Completing its flagship waterless blood purifying device to replace outdated dialysis machines.
Developing an implantable artificial kidney using the same waterless technology.
Progressing several related renal care products currently in development.

EXPERT COLLABORATION

US Kidney Research Corporation’s innovations are backed by a distinguished research team from the University of Arkansas (UA) and Dr. Ira Kurtz, the Chief of Nephrology at UCLA, who serves as the Corporation’s science/medical advisor and active board member. Dr. Kurtz, a leading expert in kidney disease, works alongside Dr. Jamie Hestekin and the UA team to drive progress toward a viable, long-term solution for kidney disease patients.

ABOUT US:

US Kidney Research Corporation (USKRC) is at the forefront of artificial kidney research and development. Acknowledged by leading organizations such as the American Society of Nephrology (ASN), KidneyX, and the US Department of Health and Human Services (HHS), USKRC is transforming the future of kidney care. By pioneering new standards in treatment, USKRC is bringing hope for a future beyond dialysis. Established in 2015, USKRC is registered as a C-Corporation in Delaware.

Learn more: https://www.uskidneyresearchcorp.com/

MEDIA CONTACT:
Roland Ludlow
US Kidney Research Corporation
EMAIL: contact@uskidneyresearchcorp.com
PHONE: 1-800-674-8904

NEWS SOURCE: US Kidney Research Corporation

This press release was issued on behalf of the news source (US Kidney Research Corporation), who is solely responsible for its accuracy, by Send2Press Newswire. Image, if any, was provided by the news source and not this website or the wire service. Information is believed accurate, as provided by the news source, but is not guaranteed.

To view the original story, visit: https://www.send2press.com/wire/us-kidney-research-corp-advances-toward-implantable-artificial-kidney/

ROSEVILLE, Calif. /ScoopCloud/ -- US Kidney Research Corporation (USKRC) is delighted to announce new groundbreaking research as part of a contract with the University of Arkansas (U of A) resulting in the development of an ultrafiltration membrane with diverse filtering applications for medical and non-medical devices. This remarkable membrane represents a significant advancement, particularly in the field of dialyzers, the filtration device used in hemodialysis machines to remove toxins, promising improved dialysis performance and enhanced ultrafiltration flux.

The recently published research in Scientific Reports (https://www.nature.com/articles/s41598-023-37765-y) unveils a novel membrane created through a tempo cellulosic oxidation process and cast using ionic liquids. Notably, the membrane showcases exceptional biocompatibility, the ability to clear potential uremic toxins, and excellent stability. Its unique structure, characterized by the alignment of fibers after casting, leads to an extraordinarily high flux and substantial BSA rejection in ultrafiltration mode, surpassing the performance of traditional dialysis membranes.

"We were highly impressed by the membrane's behavior and performance; the fiber alignment in the final structure allows for superior functionality compared to conventional dialysis membranes," expressed Jamie Hestekin, one of the lead researchers at U of A.

As part of this concerted effort, USKRC has secured worldwide rights for the patented U of A membrane in all biomedical applications. USKRC's founder and CEO Roland Ludlow, revealed that the corporation intends to explore sublicensing partnerships both domestically and internationally, with the aim of expediting the introduction of this cutting-edge membrane technology to the market, enabling its use in dialysis and other relevant applications.

Dr. Ira Kurtz, Chief of Nephrology at UCLA, who is an author on the Scientific Reports paper and serves as the lead medical/scientific advisor to USKRC commented, "This new membrane chemistry could be a game changer in the care of renal patients."

USKRC is actively engaged in several other research projects, including the development of a waterless portable blood purifying device that could potentially replace current dialysis machines, an implantable artificial kidney, and a coating to prevent blood coagulation within medical device tubing and catheters. The company has solidified its position as a leader in renal therapy research, earning prestigious recognition as a two-time winner of the KidneyX contest, sponsored by the American Society of Nephrology and the US Department of Health and Human Services. Monetary awards for KidneyX were generously provided by the US Congress and the American Society of Nephrology.

About US Kidney Research Corporation:

US Kidney Research Corporation (formerly Curion Research Corporation), is an award-winning company incorporated in Delaware (C-Corp), founded in June, 2015. The company is creating the world's first waterless blood purification technology for use in a portable device and ultimately an implantable artificial kidney, as well as other novel technologies to improve the lives of patients with end stage renal disease (ESRD) or acute kidney injury (AKI). US Kidney Research Corporation has patents for its waterless blood purifying technology in USA, Japan, India, S. Korea, China, along with 17 European Unitary patent member countries.

More information: https://www.uskidneyresearchcorp.com/

US Kidney Research Corporation (USKRC) is delighted to announce new groundbreaking research as part of a contract with the University of Arkansas (U of A) resulting in the development of an ultrafiltration membrane with diverse filtering applications for medical and non-medical devices.

Related link: https://www.uskidneyresearchcorp.com/

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Tag Archives: dialysis

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